Combining suitable national conditions with advanced technologies is essential in the production of high-quality pesticide intermediates. There are often multiple technological routes available, and selecting the most appropriate one is crucial for competitiveness. While adopting advanced foreign technologies can be beneficial, it's not always easy to master them. Therefore, implementing applicable and locally adaptable technologies plays a vital role in the industry.
For instance, isopropylaniline serves as an important intermediate in the production of isoproturon, which was once imported from abroad. In foreign countries, this compound is typically produced through the amination of isopropylphenol, a process that is relatively simple but requires precise control and expertise. In contrast, earlier domestic approaches involved using o-isopropylisopropylnaphthalene obtained from the nitration of isopropylbenzene, followed by separation of the para and ortho positions. However, after years of research and development, no effective solution was found.
Currently, the separation of nitro compounds is achieved through fractional distillation, allowing for the isolation of monoisopropyl nitrobenzene and o-isopropyl nitrobenzene. The former can be reduced to p-isopropylaniline, an essential intermediate in pesticide manufacturing, while the latter can be used to produce o-isopropylaniline, which is particularly useful in controlling pests such as wax and leafhoppers. These methods reflect the successful integration of locally adapted technologies, demonstrating how domestic innovation can effectively meet industrial needs without relying solely on foreign techniques.
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